Selected list of publications

1. Motyka, K.; Hlavac, J.; Soural, M.; Hradil, P.; Krejci, P.; Kvapil, L.; Weiss, M. Fluorescence properties of some 2-(4-amino-substituted-3-nitrophenyl)-3-hydroxyquinolin-4(1H)-ones. Tetrahedron Lett. 2011, 52 (6), 715-717.

2. Soural, M.; Hlavac, J.; Funk, P.; Dzubak, P.; Hajduch, M. 2-Phenylsubstituted-3-Hydroxyquinolin-4(1H)-one-Carboxamides: Structure-Cytotoxic Activity Relationship Study. ACS Combinatorial Science 2011, 13, 39-44.

3. Koci, J.; Krchnak, V. Solid-Phase Synthesis and Chemical Properties of 2-(2-Amino/Hydroxyethyl)-1-Aryl-3,4-Dihydropyrazino[1,2-b]Indazol-2-Iums. J. Comb. Chem. 2010, 12, 168-175.

4. Koci, J.; Oliver, A. G.; Krchnak, V. Unprecedented Rearrangement of 1,2,3,4-Tetrahydropyrazino[1,2-b]Indazole Oxides to 2,3-Dihydro-1H-Imidazo[1,2-b]Indazoles. J. Org. Chem. 2010, 75, 502-505.

5. Soural, M.; Hlavac, J.; Krchnak, V. Linkers for Solid-Phase Peptide Synthesis. In Solid-Phase Peptide Synthesis; Hughes, A., Ed.; Willey-VCH: 2010.

6. Cankarova, N.; Hlavac, J.; Krchnak, V. Recent Synthetic Approaches to 1H- and 2H-Indazoles. A Review. Organic Preparations and Procedures International 2010, 42, 433-465.

7. Krupkova, S.; Slough, G. A.; Krchnak, V. Synthesis of Quinazolines From N-(2-Nitrophenylsulfonyl)Iminodiacetate and ?-(2-Nitrophenylsulfonyl)Amino Ketones Via 2H-Indazole 1-Oxides. J. Org. Chem. 2010, 75, 4562-4566.

8. Brulikova, L.; Dzubak, P.; Hajduch, M.; Lachnitova, L.; Kollareddy, M.; Kolar, M.; Bogdanova, K.; Hlavac, J. Synthesis of 5-[alkoxy-(4-nitro-phenyl)-methyl]-uridines and study of their cytotoxic activity. Eur. J. Med. Chem. 2010, 45 (9), 3588-3594.

9. Motyka, K.; Hlavac, J.; Soural, M.; Funk, P. Fluorescence properties of 2-aryl-3-hydroxyquinolin-4(1H)-one-carboxamides. Tetrahedron Lett. 2010, 51 (38), 5060-5063.

10. Vankova, B.; Hlavac, J.; Soural, M. Solid-Phase Synthesis of Highly Diverse Purine-Hydroxyquinolinone Bisheterocycles. J. Comb. Chem. 2010, 12 (6), 890-894.

11. Hradil, P.; Hlavac, J.; Soural, M.; Hajduch, M.; Kolar, M.; Vecerova, R. 3-Hydroxy-2-phenyl-4(1H)-quinolinones as Promising Biologically Active Compounds. Mini-Rev. Med. Chem. 2009, 9 (6), 696-702.

12. Krupkova, S.; Soural, M.; Hlavac, J.; Hradil, P. Solid-Phase Synthesis of 3-Hydroxy-6-Nitroquinolin-4(1H)-ones with Two Diversity Positions. J. Comb. Chem. 2009, 11 (6), 951-955.

13. Papouskova, B.; Bednar, P.; Styskala, J.; Hlavac, J.; Bartak, P.; Lemr, K. Mass spectrometry as a tool for characterization of N,N-dialkylaminoethane-2-thiols - precursors and degradation products of chemical warfare agents. J. Mass. Spectrom. 2009, 44 (11), 1604-1612.

14. Soural, M.; Hlavac, J.; Hradil, P.; Hajduch, M. Efficient Synthesis and Cytotoxic Activity of Some Symmetrical Disulfides Derived from the Quinolin-4(1H)-one Skeleton. Eur. J. Org. Chem. 2009, (23), 3867-3870.

15. Bouillon, I.; Soural, M.; Miller, M. J.; Krchnak, V. Resins With Identical Specifications Are Not Identical. Identifying a Useful Solid-Phase Resin. J. Comb. Chem. 2009, 11, 213-215.

16. Pudelova, N.; Krchnak, V. Efficient Traceless Solid-Phase Synthesis of 3,4-Dihydropyrazino[1,2-b]Indazoles and Its 6-Oxides. J. Comb. Chem. 2009, 11, 370-374.

17. Koci, J.; Pudelova, N.; Krchnak, V. Polymer-Supported ?-Acylamino Ketones: Preparation and Application in 1,2,4-Trisubstituted-1H-Imidazole Synthesis. J. Comb. Chem. 2009, 11, 397-402.

18. Pudelova, N.; Krchnak, V. Multiplicity of Diverse Heterocycles From Polymer-Supported ?-Acylamino Ketones. J. Comb. Chem. 2009, 11, 851-859.

19. Yang, B.; Lin, W.; Krchnak, V.; Miller, M. J. Retro Iminonitroso Diels-Alder Reactions: Interconversion of Nitrosocycloadducts. Tetrahedron Lett. 2009, 50, 5879-5883.

20. Krchnak, V.; Moellmann, U.; Dahse, H.-M.; Miller, M. J. Solid-Supported Nitroso Hetero Diels-Alder Reactions. 1. Acylnitroso Dienophiles: Scope and Limitations. J. Comb. Chem. 2008, 10, 94-103.

21. Krchnak, V.; Moellmann, U.; Dahse, H.-M.; Miller, M. J. Solid-Supported Nitroso Hetero Diels-Alder Reactions. 2. Arylnitroso Dienophiles: Scope and Limitations. J. Comb. Chem. 2008, 10, 104-111.

22. Krchnak, V.; Moellmann, U.; Dahse, H.-M.; Miller, M. J. Solid-Supported Nitroso Hetero Diels-Alder Reactions. 3. Acid-Mediated Transformation of Cycloadducts by Scission of the Oxazine C-O Bonds. J. Comb. Chem. 2008, 10, 112-117.

23. Bouillon, I.; Soural, M.; Krchnak, V. Resin Capsules: Permeable Containers for Parallel/Combinatorial Solid-Phase Organic Synthesis. J. Comb. Chem. 2008, 10, 714-720.

24. Soural, M.; Bouillon, I.; Krchnak, V. Combinatorial Libraries of Bis-Heterocyclic Compounds With Skeletal Diversity. J. Comb. Chem. 2008, 10, 923-933.

25. Krchnak, V.; Waring, K. R.; Noll, B.; Moellmann, U.; Dahse, H.-M.; Miller, M. J. Evolution of Natural Product Scaffolds by Acyl- and Arylnitroso Hetero Diels-Alder Reactions: New Chemistry on Piperine. J. Org. Chem. 2008, 73, 4559-4567.

26. Bouillon, I.; Zajicek, J.; Pudelova, N.; Krchnak, V. Remarkably Efficient Synthesis of 2H-Indazole 1-Oxides and 2-H-Indazoles Via Tandem Carbon-Carbon Followed by Nitrogen-Nitrogen Bonds Formation. J. Org. Chem. 2008, 73, 9027-9032.

27. Papouskova, B.; Bednar, P.; Frysova, L.; Styskala, J.; Hlavac, J.; Bartak, P.; Ulrichova, J.; Jirkovsky, J.; Lemr, K. Mass spectrometric study of selected precursors and degradation products of chemical warfare agents. J. Mass. Spectrom. 2007, 42 (12), 1550-1561.

28. Spacilova, L.; Dzubak, P.; Hajduch, M.; Krupkova, S.; Hradil, P.; Hlavac, J. Synthesis and cytotoxic activity of various 5-[alkoxy-(4-nitro-phenyl)-methyl]-uracils in their racemic form. Bioorg. Med. Chem. Lett. 2007, 17 (23), 6647-6650.

29. Soural, M.; Krchnak, V. Efficient Solid-Phase Synthesis of 2-Substituted-3-Hydroxy-4(1H)-Quinolinone-7-Carboxamides With Two Diversity Positions. J. Comb. Chem. 2007, 9, 793-796.

30. Bouillon, I.; Krchnak, V. Efficient Solid-Phase Synthesis of 3-Substituted-5-Oxo-5H-Thiazolo[2,3-b]Quinazoline-8-Carboxamide Under Mild Conditions With Two Diversity Positions. J. Comb. Chem. 2007, 9, 912-915.

31. Hradil, P.; Grepl, M.; Hlavac, J.; Soural, M.; Malon, M.; Bertolasi, V. Some new routes for the preparation of 3-amino-2-phenyl-4(1H)-quinolinones from anthranilamides. J. Org. Chem. 2006, 71 (2), 819-822.

32. Soural, M.; Hlavac, J.; Hradil, P.; Frysova, I.; Hajduch, M.; Bertolasi, V.; Malon, M. Synthesis and cytotoxic activity of substituted 2-phenyl-3-hydroxy-4(1H)-quinolinones-7-carboxylic acids and their phenacyl esters. Eur. J. Med. Chem. 2006, 41 (4), 467-474.

33. Stanger, K. J.; Krchnak, V. Polymer-Supported N-Derivatized-O-Linked Hydroxylamine for Concurrent Solid-Phase Synthesis of Diverse N-Alkyl and N-H Hydroxamates. J. Comb. Chem. 2006, 8, 435-439.

34. Stanger, K. J.; Krchnak, V. Incorporation of the Wang Linker Upon Cleavage From Polystyrene-Based Resin to Form O-(4-Hydroxy)Benzyl Derivatives. J. Comb. Chem. 2006, 8, 652-654.

35. Stanger, K. J.; Sliva, D.; Jiang, J.; Krchnak, V. Synthesis and Screening of N-Alkyl Hydroxamates for Inhibition of Cancer Cell Proliferation. Comb. Chem High Throughput Screen. 2006, 9, 651-661.

36. Krchnak, V.; Zajicek, J. Application of a Dual Linker With a Reference Cleavage Site to Discover a New Reaction Between Amines and N-Hydroxyphthalimide. J. Comb. Chem. 2005, 7, 523-525.

37. Lemr, K.; Sevcik, J.; Hlavac, J. Retention of 3,5-dinitrobenzoyl derivatives of linear alcohol polyethoxylates in reversed-phase liquid chromatographic system with acetonitrile-water mobile phase. J. Chromatogr. A 2003, 1021 (1-2), 19-24.

38. Bednar, P.; Lemr, K.; Bartak, P.; Sevcik, J.; Hlavac, J.; Styskala, J.; Wiedermannova, I.; Stransky, Z. Capillary electrophoresis/mass spectrometry: a promising tool for the control of some physiologically hazardous compounds. I - Derivatives of 3-quinuclidinol. J. Mass. Spectrom. 2002, 37 (12), 1213-1218.